BackgroundDespite the latest advances in prenatal diagnosis and postnatal embolization procedures, intracranial arteriovenous shunts (AVSs) are still associated with high mortality and morbidity rates.Our aim was to evaluate the presentation and clinical course, the neurodevelopmental outcome, and the genetic findings of neonates with AVSs.MethodsI
Activin A targets extrasynaptic NMDA receptors to ameliorate neuronal and behavioral deficits in a mouse model of Huntington disease
Cortical-striatal synaptic dysfunction, including enhanced toxic signaling by extrasynaptic N-methyl-d-aspartate receptors (eNMDARs), precedes neurodegeneration in Huntington disease (HD).A previous study showed Activin A, whose transcription is upregulated by calcium influx via synaptic NMDARs, suppresses eNMDAR signaling.Therefore, we examined th
Design and development of a laboratory for the study of PEMFC system for marine applications
Climate change is driving the introduction of strict emission limits in the shipping sector favoring the introduction of alternative fuels, among which hydrogen.While the storage energy density of this energy vector is a key challenge that makes way to a variety of different solutions, from fossil fuel reformers to sodium borohydride systems, fuel
Valuable Public Speaking Skills for Legal Professionals
In the constant endeavour to improve their public speaking skills, legal DSP professionals must be aware of the main aspects that they have to control and of the framework that they may use for that purpose.The elements of oral communication, politeness strategies, persuasion strategies, the main coordinates of verbal and nonverbal communication ar
Characterization and efficacy against carbapenem-resistant Acinetobacter baumannii of a novel Friunavirus phage from sewage
Carbapenem-resistant Acinetobacter baumannii (CRAB) has become a new threat in recent years, owing to its rapidly increasing resistance to antibiotics and new effective therapies are needed to combat this pathogen.Phage therapy is considered to be the most promising alternative for treating CRAB infections.In this study, a novel phage, Ab_WF01, whi